In many fillers, the main constituent is hyaluronic acid (also known as hyaluronan or HA), which is a substance found naturally in our connective tissue, skin, and nerve tissues. HA keeps our skin soft and gives fluidity to our joints. In HA-based dermal fillers, HA chains are bound by with cross-links, which give it a gel-like consistency. They are commonly used in treatments of folds, lines and wrinkles, as well as enhancement and volume creation in lips, cheeks, chins, and noses.

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