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For Overall Skin Rejuvenation

Effectively Reduces Signs of Ageing and Improves Skin Radiance & Complexion

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What is Rejuran Needleless?

Needleless Rejuran is a new innovative concept introduced to the aesthetic world where Rejuran, a popular skin healing serum, is delivered deep into the dermis without hurting the surrounding skin cells and tissues via a non-invasive method.

This clinically-proven procedure provides instant results with a transdermal delivery system to effectively administer Rejuran with no needles, no pain and no downtime.


Non-invasive and needleless medical-facial


Improve skin cells with biocompatible DNA


Improvement in pore size and acne scars


Increased skin elasticity and firmness


Increased skin hydration and collagen boost

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Natural visible glow with youthful, radiant skin

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What is Rejuran?

Rejuran is a skin healing treatment that has surged in popularity in recent years especially in South Korea as well as other Asian countries such as Singapore.

It effectively reduces and heals signs of ageing by leaving the skin smoother, refreshed, and more hydrated by reactivating the skin’s healing ability to restore its own collagen structure. 

Due to the unique properties of c-PDRN paired with Hyaluronic Acid, it offers multiple benefits to the skin.

When Rejuran is delivered into the dermis, it helps to improve the skin’s collagen production as well as to brighten up the skin tone, triggering an improvement in the condition of ageing & the biological condition of damaged skin as well as triggering cell renewal. The key ingredients help in bringing about elastin and collagen growth.


Benefits of Rejuran Needleless

As we age, our skin produces less collagen and cell renewal cycle slows from 28 days to as many as 50 days, resulting in dull, sagging, damaged skin.


c-PDRN® contains naturally occurring growth factors that stimulates cell renewal, this helps promote skin rejuvenation and improves the appearance of damaged skin, restoring the look of skin’s elasticity, firmness and radiance.

  • Effectively hydrates skin

  • Lightens hyperpigmentation

  • Improves skin elasticity

  • Improves collagen & elastin scaffolding structure

  • Evens out skin tone

  • Improves acne-prone skin

  • Reduces fine lines & wrinkles

  • Fights free radicals

  • Visible same-day results


Key Ingredients of Rejuran Needleless

The below ingredients, in combination, normalises the skin regeneration cycles, inhibits melanin production & accumulation, and stimulates the skin’s own collagen production.

It replenishes the skin from the inside out and leave it feeling dewy, glowing, hydrated, supple, and soft


  • 670 times smaller than the skin’s pore for an enhanced rate of skin absorption

  • Powerful and natural skin-healing ingredient for cell growth and tissue regeneration

  • Increases the metabolic activity of fibroblasts, acting as a scaffolding for cells and cellular matrix to grow.

Hyaluronic Acid

  • Functions to retain water for your skin to be hydrated and plump

  • Reduces free radicals that result in skin ageing and protects the skin from UV rays

  • Component of the ECM contributes to cell proliferation and migration for the re-epithelisation of the skin


  • A superb skin softener known for its moisturising and soothing properties

  • Same biological activity as vitamin B5, which is essential for normal metabolism and hormone production

Vitamin C

  • Key to the production of collagen and elastin in the skin

  • Essential nutrient required for neurotransmitter function with preventative benefits

  • A powerful antioxidant causing an anti-inflammatory response

  • Helps to improve wrinkles, uneven skin tone, and moisture

GSH Antioxidant

  • Tripeptide consisting of 3 amino acids (Glycine, Glutamic acid and Cystein) Mediates the mechanism for switching from eumelanin to pheomelanin production and regulates collagen production

  • Brightens skin and inhibits melanin production

  • Lightens hyperpigmentation

Anti-Pigmentation Agent

  • A superb skin softener known for its moisturising and soothing properties

  • Inhibits melanogenesis by activating the autophagy system mediating a decrease in melanin synthesis

📹 Watch our process!

  • What skin type is Multi-Action Cream suitable for?
    Skin types showing signs of significant aging: loss of elasticity and facial definition, puffiness, decreased skin density, pigmentation It is not recommended for patients with acne-prone skin. It is a corrective treatment, not a moisturizer. Added moisturizer could be required, or use CALECIM® Professional Restorative Hydration Cream after application.
  • What skin type is Restorative Hydration Cream suitable for
    Skin types showing signs of dehydration: fine lines with dull texture and uneven skin tone. Premature-aging due to dryness or environmental exposure It is not recommended for patients with acne-prone skin. When used in conjunction with CALECIM® Professional Multi-Action Cream, skin is ensured of the optimal hydration levels required for healthy self-healing and rejuvenation.
  • I have oily/acne-prone skin, is CALECIM® Professional suitable for me?"
    We recommend that you treat the acne before using CALECIM® Professional products.
  • Can I apply CALECIM® Professional Serum and Multi-Action Cream together?
    Yes you can. Apply Professional Serum after cleansing and toner, followed by Multi-Action Cream onto the face, up to hairline, around eye contour area, extending to the neck and décolleté. Restorative Hydration Cream can be used after as a moisturizer We find that improvement is most obvious around the eye, cheek and jowl area, hence it is important to remind patients to apply the cream to a level below the jawline.
  • Does Multi-Action Cream act as a moisturizer?
    Multi-Action Cream is mildly moisturising. For those with oily skin, Multi-Action Cream is sufficiently moisturizing without additional application of moisturizer. For other skin types (dry or combination skin), we recommend that you apply your own moisturiser after Multi-Action Cream, or use Restorative Hydration Cream.
  • Can I apply Multi-Action Cream around my eyes?
    Yes you can. For the upper eyelids, restrict application to the area just under the eyebrows. Please ensure Multi-Action Cream does not enter eyes as it may be mildly irritating.
  • Does CALECIM® Professional products contain preservatives?
    Yes they contain proprietary preservatives.
  • Why is Multi-Action Cream consistency different in this bottle?
    CALECIM® Professional is made as naturally as possible. It is a biological product that is derived from stem cells. The consistency of the creams may vary from batch to batch, however, this will not affect the efficacy of the product.
  • Have you heard of any bad reactions to this product?
    We have had thousands of patients use our products which have been dispensed by doctors around the world. We have not received news of any significant adverse reactions. Should there be any adverse reaction, the patient should stop using the product, and this is recommended for any cosmetic product.

experience rejuran

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rejuran healer

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rejuran s (scar)

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Take the leap

and start your aesthetic journey today

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