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Bio-Remodelling Injectable Skincare

Improve and Restore Firmness of the Skin with a hydrating Hyaluronic Acid Treatment

What is Profhilo?

Profhilo® is the first of its kind revolutionary bio-remodelling "injectable skincare" that addresses skin laxity and signs of ageing through the bio-stumulation of collagen, elastin and adipocytes (fats) stem cells that gets lost through the impact of skin ageing.

Profhilo is made with the patented NAHYCO® technology with one of the highest concentrations of Hyaluronic Acid which helps to boost and hydrate the skin, but also assists in remodelling ageing and sagging tissue.

The most common areas of treatment include the face and neck and can also be used for the décolletage, hands, arms, knees and abdomen area where it would effectively treat skin laxity. The treatment is suitable for men and women as well as offering skin benefits for patients of all ages.


New anti-aging approach with innovative technology that targets from the inside out


Uses 100% pure hyaluronic acid


High hyaluronic concentration using 32mg of hyaluronic acid (high molecular weight) and 32mg of hyaluronic acid (low molecular weight)


Intervenes the process of aging tissue, biostimulates elastin and collagen


Addresses signs of skin aging naturally


12X increase

of collagen and elastin in skin

8X more

lasting in the skin than regular non cross-linked hyaluronic acid

20% increase

in skin hydration

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How does Profhilo work?

Ultra-pure hyaluronic acid is precisely injected into the area being treated.

Unlike wrinkle reducing and dermal filler treatments, Profhilo® stimulates collagen and elastin, attracting water in the deeper layers of the skin.

As a stabilised product, the activity on dermal cells will last longer than that of a non-stabilised gel. During this time the stimulation of four different types of collagen and elastin takes place by slow release of hyaluronic acid.

The stimulation results in significant tissue improvement. Therefore we cannot say that  Profhilo® is a skin booster as it also has a significant tightening / lifting effect on the tissue.


Benefits of Profhilo

  • Boosts collagen and elastin solution

    • Various types of elastin and collagen at different levels of the skin are stimulated to give the skin a firmer, tighter, and lifted effect.

  • Keeps the skin hydrated

    • The H-HA component of hyaluronic acid that is slowly released keeps the epidermis well-hydrated.

  • Helps treat acne scars

    • Profhilo also contributes to the tissue repair process of the skin which makes it suitable for treating acne scars.

  • Maintains the health of the skin

    • The ingredients of Profhilo relieve and prevent the visible signs of ageing, and it also keeps the skin healthy.

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Treatment Procedure

Your consultation will begin with a friendly and detailed assessment to understand what you would like to achieve with your treatment.

All patients undergo a thorough assessment of skin tone, texture and elasticity followed by facial photography and videography.

Profhilo injections are carried out with a premium micro-needle, which does not require anaesthesia, but this may be provided if one prefers at no extra cost. We also provide topical numbing cream that is available upon request to reduce any pain or discomfort.

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Before and after
Profhilo treatment

The Profhilo works by stimulating collagen and elastin, increasing hydration in the deeper layers of the skin, giving your skin more of a natural glow and a distinct revitalisation. ​ Profhilo enhances tissue health and restoration.

In that sense, beyond simply being a skin booster, Profhilo also helps to tighten and lift the skin tissue aiding overall appearance, particularly for lower regions of the face.


📹 Watch our process!

  • What skin type is Multi-Action Cream suitable for?
    Skin types showing signs of significant aging: loss of elasticity and facial definition, puffiness, decreased skin density, pigmentation It is not recommended for patients with acne-prone skin. It is a corrective treatment, not a moisturizer. Added moisturizer could be required, or use CALECIM® Professional Restorative Hydration Cream after application.
  • What skin type is Restorative Hydration Cream suitable for
    Skin types showing signs of dehydration: fine lines with dull texture and uneven skin tone. Premature-aging due to dryness or environmental exposure It is not recommended for patients with acne-prone skin. When used in conjunction with CALECIM® Professional Multi-Action Cream, skin is ensured of the optimal hydration levels required for healthy self-healing and rejuvenation.
  • I have oily/acne-prone skin, is CALECIM® Professional suitable for me?"
    We recommend that you treat the acne before using CALECIM® Professional products.
  • Can I apply CALECIM® Professional Serum and Multi-Action Cream together?
    Yes you can. Apply Professional Serum after cleansing and toner, followed by Multi-Action Cream onto the face, up to hairline, around eye contour area, extending to the neck and décolleté. Restorative Hydration Cream can be used after as a moisturizer We find that improvement is most obvious around the eye, cheek and jowl area, hence it is important to remind patients to apply the cream to a level below the jawline.
  • Does Multi-Action Cream act as a moisturizer?
    Multi-Action Cream is mildly moisturising. For those with oily skin, Multi-Action Cream is sufficiently moisturizing without additional application of moisturizer. For other skin types (dry or combination skin), we recommend that you apply your own moisturiser after Multi-Action Cream, or use Restorative Hydration Cream.
  • Can I apply Multi-Action Cream around my eyes?
    Yes you can. For the upper eyelids, restrict application to the area just under the eyebrows. Please ensure Multi-Action Cream does not enter eyes as it may be mildly irritating.
  • Does CALECIM® Professional products contain preservatives?
    Yes they contain proprietary preservatives.
  • Why is Multi-Action Cream consistency different in this bottle?
    CALECIM® Professional is made as naturally as possible. It is a biological product that is derived from stem cells. The consistency of the creams may vary from batch to batch, however, this will not affect the efficacy of the product.
  • Have you heard of any bad reactions to this product?
    We have had thousands of patients use our products which have been dispensed by doctors around the world. We have not received news of any significant adverse reactions. Should there be any adverse reaction, the patient should stop using the product, and this is recommended for any cosmetic product.

Take the leap

and start your aesthetic journey today

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